Set to open in 1964, the six-story 160 unit Wheaton Motor Lodge remained a Howard Johnson's until the early 1980s. Boasting traditional HoJo's amenities, it was considered an upscale Howard Johnson's.

The site featured an in-the-building lobby and a separate Nims-type restaurant. By the 2000s, the Restaurant had been converted into a bank branch, but by Phil Edwards visit in 2003 the bank had been closed. Additionally, the Lodge itself had become the Ambassador Apartments with La Caverna Restaurant occupying a part of the ground floor.